Fig. 5
MMC decreased vascular permeability. MVNs cultured under crowded (+ MMC), and control conditions (no MMC) were perfused with FITC-PVP (40 kDa, A & B) or Texas RedTM-BSA (C & D), respectively, supplemented culture medium. (A) and (C) Representative frame from live cell imaging showing the perfusion of MVN from one medium channel to the other on day 4. Scale bar = 100 μm. (B ) and (D) Permeability coefficient of MVNs for FITC-PVP (40 kDa) and Texas RedTM-BSA, respectively, cultured under control and crowded conditions on day 4. **, p < 0.01; ****, p < 0.0001