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Fig. 12 | Biomaterials Research

Fig. 12

From: Emerging biomaterials for tumor immunotherapy

Fig. 12

Schematic diagram of polysaccharide or silk fibroin based biomaterials for tumor immunotherapy. A Schematic diagram of preparation and action steps of NOCC-CpG/OX-M hydrogel (Ncom Gel) vaccine. B Antitumor efficacy of the Ncom Gel vaccine in C57BL/6 melanoma mice. (a) Average tumor growth curves of B16F10-OVA tumor-bearing mice after treatment. (b) Survival curves of mice after treatments. (c) Body weight curves during the treatment. (d) Individual mouse tumor growth curves with different treatments. (Reproduced with permission from [111] Copyright © 2021, Theranostics) C. Schematic illustration of the local chemotherapy-therapeutic EVs-synergistic immunotherapy. D Synergistic efficacy of aPD1 & CCs-SF/DOX NPs to trigger antitumor immune response. (a) Representative pictures of tumors on Balb/c mice at day 20. (b) Tumor growth curves and (c) body weight changes of Balb/c mice. (Reproduced with permission from [113]  Copyright © 2020, Royal Society of Chemistry) [113]

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