Fig. 5
From: Advanced pathophysiology mimicking lung models for accelerated drug discovery
The impedance measurement of CNBio NHBE-NHLF models was performed every 2–3 days during 24 days. The left panels indicated the TEER value and the right panels indicated cell capacitance. The TEER value (from Day 3 to Day 15) and cell capacitance (from Day 13 to Day 24) were presented for (A) CNBio NHBE-NHLF coated with collagen on the Corning insert (B) CNBio NHBE-NHLF coated with collagen on the CellQart insert (C) CNBio NHBE-NHLF coated with fibronectin on the Corning insert (D) CNBio NHBE-NHLF coated with collagen on the Corning insert. n = 3. E 3D topographical AFM images and linear regression analysis of the stiffness of the Corning and CellQart inserts. The stiffness analyses of the Corning and CellQart inserts were generated from the force-volume map of the Corning insert (800 points) and 40 individual force-distance curves of the CellQart insert