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Fig. 7 | Biomaterials Research

Fig. 7

From: De novo design of a novel AIE fluorescent probe tailored to autophagy visualization via pH manipulation

Fig. 7

A Simple schematic illustration of autophagy activation in the APAP-induced liver injury model and schematic presentation of the construction of mice model and relative experiment method; B CLSM images of the liver tissue obtained from mice injected with ASMP-AP. λex = 405 nm, λem = 560–620 nm. C) The quantified fluorescence intensity of ASMP-AP in panel B. Error bars represent standard deviation (SD) of ten ROIs. Statistical analyses were performed with One-way Anova. ****: p < 0.0001. D Representative histological analysis of the livers of mice with different treatments, saline, APAP and APAP + NAC. Scale bar, 100 µm

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