Fig. 4

Characterization and multiple dimension reduction of plasma exosome proteins. A Representative western blots of the CD63 protein in 15 serum exosome samples among the three groups B The number of quantified proteins in the three sample groups (C) Venn diagram of proteins between Vesiclepedia in Homo sapiens and this study result. D Cellular component of GO of quantified proteins in FunRich (version 3.1.3). E Principal component analysis of the three groups by the proteins. F The loadings of the top 10 and bottom 10 proteins of principal component 1. NB: The three groups are P: Parkinson’s disease (N = 10); M: multiple sclerosis (N = 10); D: dementia (N = 10).