Fig. 5

In vivo antitumor and metastasis of RD@MBs + αPD-L1 in murine 4T1 and colorectal cancer models. a Schematic illustration of the experimental schedule on tumor bearing mice. b Average and individual tumor growth curves of 4T1 orthotopic tumor bearing mice primary and distant tumor after different treatments. c Survival rate of mice after different treatment on 4T1 orthotopic tumor bearing mice. d Average and individual tumor growth curves of CT26 subcutaneous tumor bearing mice primary and distant tumor after different treatments. e Survival rate of mice after different treatments on CT26 subcutaneous tumor bearing mice. Data are expressed as mean ± SD (n = 5). Statistical significances were calculated via Student’s t test, *p < 0.05, **p < 0.01 and ***p < 0.001