Fig. 4

RD@MBs promoted DC maturation and stimulated the secretion of proinflammatory cytokines in vivo. a Schematic diagram of the experimental procedure to assess the in vivo DC maturation. b-g DC maturation (CD11c⁺CD80⁺CD86⁺) in tumor, tumor-draining lymph nodes and spleen. h-i IL-6 and TNF-α levels in serum, analyzed by ELISA. Data are expressed as mean ± SD (n = 3). Statistical significances were calculated via Student’s t test, *p < 0.05, **p < 0.01 and ***p < 0.001