Fig. 9

In vivo immunofluorescent analyses of each animal group for the related markers. The expression of (A) tyrosine hydroxylase positive (TH+) dopaminergic neurons in the substantia nigra pars compacta (SNpc), (B) TH+ dopaminergic fibers in the striatum, and (C) glial fibrillary acidic protein positive (GFAP+) astrocytes in the PD rat striatum were investigated at 14 days after surgery. Green color represents the indicated marker and blue color represents the nucleus. The fluorescent intensities were quantified and presented as graphics for (D) TH+ dopaminergic neurons in the SNpc, (E) TH+ dopaminergic fibers in the striatum, and (F) GFAP+ astrocytes in the striatum of each group. *p < 0.05, ***p < 0.001, and ****p < 0.0001 between the indicated groups