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Fig. 5 | Biomaterials Research

Fig. 5

From: Identification of cell-biologic mechanisms of coronary artery spasm and its ex vivo diagnosis using peripheral blood-derived iPSCs

Fig. 5

Differences in the magnitude of intracellular calcium efflux among VSA patients in response to various dosages of diverse vasodilators. By measuring intracellular calcium efflux in iPSC-derived VSMCs from VSA patients or normal subjects via our method, we evaluated changes of intracellular calcium efflux in response to various dosages (0.01, 0.05, 0.5, 1, 5, 10, 100 μM) of calcium channel blockers (Verapamil, Diltiazem) and vasodilators (Nicorandil, Molsidomine, Nitrate). The inhibitory effect of each drug differed even among VSA patients

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