Fig. 5

Reprogramming of TAM with biomaterials. a A combination of R848, which is a TLR7/8 agonist, and CDNP can decrease the tumor size. (Reproduced with permission from [36] Copyright 2019, Theranostics). b Effect of chitosan nanoparticles on reprogramming of TAMs and tumor metastasis in animals, the mouse acute lung injury model, was established (Reproduced with permission from [46] Copyright 2022, Elsevier). c Growth curves of primary tumors and distant tumors of bilateral CT26 tumor-bearing mice. Black, red, and blue arrows refer to intratumoral injection, X-ray irradiation, and intraperitoneal injection, respectively. (Reproduced with permission from [54] Copyright 2020, American Chemical Society)