Fig. 3
From: Reprogramming the tumor microenvironment with biotechnology
TLR2 and TLR3 can convert M2 into M1. a TLR-3 triggering reverts human M2 to M1. The size of the tumor is indicated in squared millimeters at different time points. (Reproduced with permission from [40] Copyright 2018, Frontiers in Immunology). b Cytokine profile of M0-, M1-, and M2-polarized macrophages following TLR ligand exposure and activation. (Reproduced with permission from [43] Copyright 2017, Arthritis Research & Therapy)