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Fig. 5 | Biomaterials Research

Fig. 5

From: A drug delivery system constructed by a fusion peptide capturing exosomes targets to titanium implants accurately resulting the enhancement of osseointegration peri-implant

Fig. 5

EXO-PEP3 enhanced osteogenesis peri-implants via targeting exosomes to the titanium surface in vivo. A Micro-CT images of reconstructed 3D models of surrounding bones (a) with or (b) without implants. (c) Local amplification of reconstructed 3D images showed the surrounding bones formation into the hole of implant. (d) The mineral density of bones surrounding the implant. B Quantity analysis for bone volume to total volume ratio (BV/TV) and bone mineral density (BMD). C Western blot analyzed the protein expression involved in the osteogenesis of the BMSCs (p < 0.05). D The RNAs expression involved in the osteogenesis of the BMSCs. The significant differences are calculated by comparing each group each other (p < 0.05)

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