Skip to main content
Fig. 7 | Biomaterials Research

Fig. 7

From: Periosteum-inspired in situ CaP generated nanocomposite hydrogels with strong bone adhesion and superior stretchability for accelerated distraction osteogenesis

Fig. 7

Proteomic and bioinformatic analysis across the PEGS/20ICPN hydrogel. a Volcano plot of the DEPs between groups. Blue points represent down-regulated proteins. Red points represent upregulated proteins. b, c GO and KEGG protein enrichment analysis. d Immunofluorescence staining of the newly formed bone with DAPI (blue), Vinculin (red), and α-actinin (red). e Relative mRNA levels of genes related to cell adhesion in all groups. f Immunofluorescence staining of the newly formed bone with DAPI (blue, nuclei), CD68 (red, a marker of macrophages), iNOS (green, a marker of M1), and ARG-1 (green, a marker of M2). Quantitation of the rate of iNOS+/CD68+ macrophages and ARG-1+ / CD68+ macrophages. g Relative mRNA levels of TNF-α, IL-1β, IL-10, and TGF-β of the newly formed bone in all groups

Back to article page

Biomaterials Research

ISSN: 2055-7124

Contact us