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Fig. 7 | Biomaterials Research

Fig. 7

From: Plasma polymerized bio-interface directs fibronectin adsorption and functionalization to enhance “epithelial barrier structure” formation via FN-ITG β1-FAK-mTOR signaling cascade

Fig. 7

Changes in the intracellular signaling of HGEs cultured on the chemical surfaces. A Number of upregulated genes of HGEs on ppAA surface in comparison to the other surfaces; B KEGG analysis of the 650 types co-upregulated genes; C the expression of AKT-mTOR signaling pathway related genes by RT-qPCR; D representative western blot images of the FAK-AKT-mTOR signaling pathway related proteins; representative western blot images of FAK-mTOR signaling related proteins of HGEs cultured on ppAA surface with and without ITGβ1 blocking antibodies (E) and FN neutralize antibodies (F). Significant differences between two groups with a p < 0.05 are presented as follows: a) versus ppAA group, b) versus ppAC group, c) versus ppME group, and d) versus control group

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