Fig. 4
From: PEG-mediated transduction of rAAV as a platform for spatially confined and efficient gene delivery
Long-term transgene expression of PEG-treated rAAV9-hSyn::EGFP in vivo. a EGFP expression in brain slices after an 8-week transduction of untreated rAAV9-hSyn::EGFP. Scale bar, 100 μm. b EGFP expression in brain slices after an 8-week transduction of 40% PEG-treated rAAV9-hSyn::EGFP. The right figure shows the zoom-in view of EGFP in the white dashed box in left figure. The white arrows indicate the positions of EGFP-positive neurons. Scale bar, 100 μm and 20 μm. c GFAP in brain slices after an 8-week transduction of untreated rAAV. Scale bars, 100 μm. d GFAP in brain slices after an 8-week transduction of 40% PEG-treated rAAV. The right figure shows the zoom-in views of GFAP in the white dashed box in left figure. The white arrows indicate the positions of EGFP-positive neurons. Scale bars, 100 μm and 20 μm