Fig. 7From: Functional insights from targeted imaging BACE1: the first near-infrared fluorescent probe for Alzheimer’s disease diagnosisEx vivo histology study of HBAE binding to BACE1 in AD and wild type mice. From left to right: heart, liver, spleen, lung, kidney and brain. According to the Figs. 6 and 7, most of compound HBAE has enter the brain, and probe is metabolized in the liver and cleared by the kidneyBack to article page