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Fig. 2 | Biomaterials Research

Fig. 2

From: Functional insights from targeted imaging BACE1: the first near-infrared fluorescent probe for Alzheimer’s disease diagnosis

Fig. 2

Illustration for the working principle of the designed NIR ratiometric fluorescent probe HBAE for the determination of BACE1 in neurons and mouse brain tissue slice. A the 3D docked conformation of the BACE1 and HBAE of the X-ray structure of BACE1. B the 2D docked conformation of the BACE1 and HBAE of the X-ray structure of BACE1 (PDB entry 5I3Y)

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