Fig. 4
a In vivo PA images of C6 tumor-bearing mice before and after intravenous injection of GOD@POMs. b Schematic illustration of the C6 tumor-bearing mice model establishment and the therapeutic process. c Photothermal heating curves and (d) corresponding IR thermal images of C6 tumor-bearing mice intravenously injected with PBS or GOD@POMs under laser irradiation (1064 nm, 1 W/cm2). e Relative tumor volume growth curves on C6 tumor-bearing mice after different treatments, including (I) Control, (II) Laser, (III) GOD, (IV) POMs, (V) GOD@POMs and (VI) GOD@POMs + Laser. f Digital photos of resected tumors from C6 tumor-bearing mice after different treatments. g Body weights of C6 tumor-bearing mice after different treatments. h H&E, Ki67 and TUNEL analysis of tumor tissues collected after various treatments. Scale bar: 100 μm. ***p < 0.001, **p < 0.01 and *p < 0.05