Fig. 4

SIRPα-v Exos alleviate WMI after ICH. A Representative images of 3D reconstruction of DTI on the 35th day post-ICH. The areas in the yellow dotted lines show the defects of white matter tracts. B Representative coronal images of the DEC map on the 35th day post-ICH. C Quantification of FA values on the ipsilateral STR on the 35th day post-ICH. Data are expressed as the ratio of FA values in the ipsilateral (lesioned) hemispheres to the FA values in the non-lesioned contralateral hemispheres (n = 12/group). D Representative images of MBP (green) immunofluorescence in the area associated with DTI (scale bar = 1 mm). E Quantification of the fluorescence intensity (CC and STR) in the area around the hematoma. Data are calculated as fold-change compared to the corresponding contralateral areas (n = 6/group). * P < 0.05, ** P < 0.01 vs. Sham group; # P < 0.05, ## P < 0.01 vs. Con group; ▲ P < 0.05, vs. NC Exo group; ns, no significance. All the data are presented as the mean ± SD. CC, corpus callosum, STR, striatum