Fig. 10

Gel:HA:PEDOT-NPs 1 × scaffold provided a diminished astrocyte reactivity around the lesion border and increased axonal migration towards the lesion site. a Representative immunofluorescence images of spinal cord tissue section labelling with NF200 (green) and GFAP (red) in rats implanted with PEDOT 1 × gel:HA:PEDOT-NPs and injured as lesion control (A-B), scale bar -1 mm. Dashed lines indicate the lesion/scaffold area and arrows indicate the periphery of GFAP reactive area. (C-D) Higher magnification of the area in rectangles in (A), scale bar -50 µm. b Quantification of the GFAP reactive area around the lesion site. c) Quantification of the number of axons from the lesion site in 200 µm distance intervals. * p < 0.05, (n ≥ 3, mean ± SD) is indicated where statistical difference is observed