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Table 1 Comparison of DCDS and other sutures with biological origin

From: Aligned nanofibrous collagen membranes from fish swim bladder as a tough and acid-resistant suture for pH-regulated stomach perforation and tendon rupture

Suture

Biological origin

Main ingredient

Tensile strength

(Mpa)

Absorbability

Histocompatibility

Characteristics

DCDS

Swim bladder from fish

Collagen

442–553

Absorbable

Good, better than gut with very mild tissue inflammation

1. Achieving multi-function with drugs.

2. Obtaining different crosslinking degree to achieve different strengths and degradability on different needs.

3. Possessing strong acid resistance;

Plain gut

Gut of mammalian

Collagen

235–413

Absorbable

Causing tissue inflammation in acute phase

Easy to break with rapid loss of strength and rapid degradation in vivo.

Chromic gut

Gut of mammalian

Collagen

224–410

Absorbable

Tissue inflammation lighter than plain gut

Comparing with plain gut, the strength maintenance in vivo is improved and degradation is slower after chrome.

Silk sutures with antibacterial and anti-inflammatory functions

Silk

Silk fibroin

399–441

Non-absorbable

Causing tissue inflammation in the beginning short term

Based on silk suture, it achieves drug release and promoting wound healing with loading drug.

Opto-Electro Sensing Sutures

Silk

Silk protein

Uncertain

(Depending on core material)

Uncertain

(Depending on core material)

Depending on core material

1. Multilayer drug loading.

2. Silk protein is only used as a coating material, and the property of the suture mostly depends on the inner core material;

Light-Activated Tissue-Integrating Sutures

Rat tail tendon

Collagen

slightly lower than PGA

Absorbable

Causing mild tissue inflammation

It can closely combine with the tissue and promote tissue healing with light activation.