Fig. 13
From: Recent advances in optical imaging through deep tissue: imaging probes and techniques
High-speed time-gated reflection matrix approaches for in vivo imaging. a Label-free volumetric images of the hindbrain of a 10-dpf larval zebrafish taken by AO-SASM. Adapted with permission from Ref [47]. b In vivo through-skull mouse brain imaging with LS-RMM. Adapted with permission from Ref. [48]. OCM: in vivo through-skull optical coherence microscopy image. LS-RMM: LS-RMM image corresponding to OCM image. Before HC: ex vivo through-skull two-photon images showing neuronal dendrites in the brain of a Thy1-EGFP line M mouse before hardware wavefront correction. After HC: two-photon images after hardware wavefront correction, corresponding to before HC images. Imaging depths: z1 = 113 ± 1.5 μm, z2 = 122 ± 1.5 μm. Adapted with permission from Ref. [48]