Fig. 2

Size and shape modulation of synthesized calcium phosphate nanoparticles (CNP) with the increase in stabilizing agent (Gelatin) during the synthesis process: (A) with 0.25 g gelatin, (B) with 0.5 g gelatin, (C) with 0.75 g gelatin, and (D) with 1 g gelatin; (E) corresponding particle size distribution (1.753 μm < 50% for 0.25 g; 1.576 μm < 50% for 0.5 g; 0.787 μm < 50% for 0.75 g; 0.296 μm < 50% for 1.0 g), (F) EDS showing Ca, P and O as major components, confirming formation of calcium phosphate nanoparticles; SEM images of cross-linked hydrogel (G) GelMA, (h) CNP (50%) GelMA, (I) CNP GelMA (solutions of 30% w/v were cross-linked with 5% w/w Irgacure 2955 for 5 min UV exposure), (J) scheme for size and shape modulation, depending on gelatin concentration and their aspect ratios with possible nucleation development