Fig. 6
From: Oxygen tank for synergistic hypoxia relief to enhance mitochondria-targeted photodynamic therapy
Potential long-term in vivo biosafety analysis of Oxygen Tank (200uL, 100μg/mL IR780, tail vein injection). a H&E staining images of major organs of the AGS-bearing mice in different treatments (PBS, PBS with laser, Oxygen Tank, IP NPs with laser, AIP NPs with laser, and Oxygen Tank with laser). The scale bar is 200 μm. b-e Hematology assay of the AGS-bearing mice in different treatments (PBS, PBS with laser, Oxygen Tank, IP NPs with laser, AIP NPs with laser, and Oxygen Tank with laser). b. WBC: white blood cell; c. LYM: lymphocytes; d. RBC: red blood cell; PLT: platelets. f-g Serum biochemical assay of the AGS-bearing mice in different treatments (PBS, PBS with laser, Oxygen Tank, IP NPs with laser, AIP NPs with laser, and Oxygen Tank with laser). f BUN: blood urea nitrogen; g Scr: serum creatinine. Data are demonstrated as mean ± SD and analyzed by the one-way ANOVA method (n = 3). N.S. means Not Significant