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Fig. 8 | Biomaterials Research

Fig. 8

From: An efficient strategy to recellularization of a rat aorta scaffold: an optimized decellularization, detergent removal, and Apelin-13 immobilization

Fig. 8

Mechanical testing of native, decellularized, and recellularized vascular tissues. Tissues elongation until the rupture is indicated as strain. Our results exhibited a reduction in the maximum strain to rupture of 0.5% SDS and CHAPS groups compared to that of native tissues (116% ± 6.79, 139.1% ± 3.24, and 164% ± 8.54%, respectively) (A). maximum force tolerated by tissues before rupture is presented as ultimate stress. Ultimate stress tolerated before rupture was significantly lower in both RRA and RRA/AP-13 groups compared to that of NRA (B) (* difference with NRA, P < 0.05; and ** difference with NRA, P < 0.01). NRA: Native Rat Aorta, SDS: Sodium Dodecyl Sulphate, CHAPS: 3-[(3-cholamidopropyl) dimethylammonio]-1-propanesulfonate, TX: Triton X-100, SDS + TX: Sodium Dodecyl Sulphate + Triton X-100, RRA: Recellularized Rat Aorta, RRA/AP-13: Recellularized Rat Aorta

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Biomaterials Research

ISSN: 2055-7124

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