Biomineralization of bone tissue: calcium phosphate-based inorganics in collagen fibrillar organic matrices

Biomaterials Research

Table 4 Ionic concentration (mM) of blood plasma and SBF studied to date

Formulation	Na⁺	K⁺	Mg²⁺	Ca²⁺	Cl⁻	HCO₃⁻	HPO₄²⁻	SO₄²⁻	Buffer
Blood plasma [138]	142.0	5.0	1.5	2.5	103.0	27.0	1.0	0.5	-
Original SBF [33]	142.0	5.0	1.5	2.5	148.8	4.2	1.0	0	Tris
Corrected (c-SBF) [139]	142.0	5.0	1.5	2.5	147.8	4.2	1.0	0.5	Tris
Tas-SBF [140]	142.0	5.0	1.5	2.5	125.0	27.0	1.0	0.5	Tris
Bigi-SBF [138]	141.5	5.0	1.5	2.5	124.5	27.0	1.0	0.5	HEPES
Revised (r-SBF) [141]	142.0	5.0	1.5	2.5	103.0	27.0	1.0	0.5	HEPES
Modified (m-SBF) [141]	142.0	5.0	1.5	2.5	103.0	10.0	1.0	0.5	HEPES
Ionized (i-SBF) [141]	142.0	5.0	1.0	1.6	103.0	27.0	1.0	0.5	HEPES

Tris tris(hydroxymethyl)aminomethane, HEPES 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid

ISSN: 2055-7124