Fig. 2

A scheme of hierarchical structure of bone tissue composed of organic and inorganic materials [19], Copyright © 2018, The American Association for the Advancement of Science. The inorganics of the mineralized collagen fibrils themselves incorporate several nested structural motifs, listed as follows in decreasing order of complexity: mineral aggregates – stacks of platelets – platelets – acicular crystals. Collagen fibrils are composed of quasi-hexagonally packed microfibrils, each of which incorporates multiple staggered triple helices that in turn are formed from repetitive chains of amino acids. Ordered and disordered motifs of bone consist of mineralized collagen fibrils that are about 120 nm thick and build a continuous network