Fig. 4
Exo-S inhibited shoulder stiffness in vivo. A Typical picture of joint capsule on HE and Masson staining (bar = 200 or 100 μm), as well as immunofluorescent staining for Col 1 and α-SMA (bar = 50 μm). Red arrow indicated nucleus, yellow line indicated the borders of joint capsule; B The quantification of capsule thickness among different groups; C Cell counts per 25 μm*25 μm; D passive ROM of the index shoulders; E and F Quantification of α-SMA and Col 1 in capsule samples. 1: group Control; 2: group Model; 3: group Model + Exolow; 4: group Model + Exohigh. *: P < 0.05 compared to group Control; ***: P < 0.001 compared to group Control; ****: P < 0.0001 compared to group Control; #: P < 0.05 compared to group Model; ##: P < 0.01 compared to group Model; ###: P < 0.001 compared to group Model