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Fig. 3 | Biomaterials Research

Fig. 3

From: si-Tgfbr1-loading liposomes inhibit shoulder capsule fibrosis via mimicking the protective function of exosomes from patients with adhesive capsulitis

Fig. 3

Exo-S relieved fibrogenesis of CDFs. A and B Proliferation was detected by Brdu assay at 24 h following TGF-β culturing or concomitant Exo-S intervention with different concentrations, and quantification. Bar = 180 μm; C Migration ability of CDFs and quantification; E Viability of CDFs determined using CCK-8 assay. F and G Collagen contraction of CDFs (red dotted circle illustrated the collagen) and quantification; H and I Immunofluorescent staining of Col 1 and α-SMA in CDFs (bar = 25 μm) and quantification; J and k Protein level of fibrotic markers in CDFs and quantification. *: P < 0.05 compared to group NC; **: P < 0.01 compared to group NC; ***: P < 0.001 compared to group NC; #: P < 0.05 compared to group TGF-β; ##: P < 0.01 compared to group TGF-β; ###: P < 0.001 compared to group TGF-β; ####: P < 0.0001 compared to group TGF-β

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