Fig. 1From: si-Tgfbr1-loading liposomes inhibit shoulder capsule fibrosis via mimicking the protective function of exosomes from patients with adhesive capsulitisResearch design of the current study. First, in the Clinical Medicine section, we collected the samples of patients included and extracted circulating exosomes for miRNAs sequencing. Then, in Basic Medicine section, we organized a series of experiments test the biological function exosomes and the contained miRNA. Finally, in the Translational Medicine Section, enlightened by the biological function of exosomal miR-142, we prepared si-Tgfbr1-loading liposomes and verified the anti-fibrotic effect, providing a potential therapy against adhesive capsulitisBack to article page