Table 4 Other metal-based hydrogels for postoperative cancer therapy
From: Enhanced postoperative cancer therapy by iron-based hydrogels
Metal | Function | Indication | Treatment strategy | Ref. |
|---|---|---|---|---|
Cu | generating ROS, killing the residual cancer cells, preventing the orthotopic tumor recurrence, and realizing local antisepsis | lung adenocarcinoma | CDT-PPT-Immunotherapy | [159] |
Mn | alleviation of tumor hypoxia; photothermal hyperthermia; anti-infection | cutaneous cancer | CDT; PPT | [160] |
Mn | Decomposing H2O2 to produce O2; PTT; loading GOx | skin tumors | PTT-Starvation therapy; | [161] |
Ge | Increasing drug-loading capacity and multi-responsive; increasing good biocompatibility, and drug-release behavior;realizing multimodal imaging-guided treatment | Breast Cancer | PPT-Chemotherapy | [162] |
Ca | enhancing the mechanical properties of the patches; reducing their swelling ratio | pancreatic cancer | Chemotherapy | [163] |
Ti | acting as photosensitizer | skin tumors | PTT-PDT | [164] |