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Fig. 9 | Biomaterials Research

Fig. 9

From: Peripheral nerve defects repaired with autogenous vein grafts filled with platelet-rich plasma and active nerve microtissues and evaluated by novel multimodal ultrasound techniques

Fig. 9

CEUS detection and VEGF mRNA analysis of nerve graft on the operated side at 12 weeks post-operation. A CEUS examination of regenerative vessels of nerve graft. The enhanced time was shown in the horizontal axis and the enhanced intensity was shown in the vertical axis. The time-intensity curves of CEUS image of nerve graft in the hollow group, PRP group, Micro-T group, Micro-T + PRP group and Autograft group were displayed. The pink and yellow ROIs represented the same two sampling frames, and they referred to repeated measurements at different parts of the nerve graft. Statistical analyses were performed by comparing the B TTP, C PI and D AUC on the CEUS in the nerve graft among groups. E Relative expression level analysis of VEGF mRNA. F Correlation analysis of the expression of VEGF mRNA and the AUC value. *P < 0.05, **P < 0.01, and n.s. not significant. CEUS contrast-enhanced ultrasonography, Micro-T microtissues, PRP platelet-rich plasma, ROI region of interest, TTP time to peak, PI peak intensity, AUC area under the curve

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Biomaterials Research

ISSN: 2055-7124

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