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Fig. 5 | Biomaterials Research

Fig. 5

From: Injection laryngoplasty of human adipose-derived stem cell spheroids with hyaluronic acid-based hydrogel improves the morphological and functional characteristics of geriatric larynx

Fig. 5

Effects of hASC spheroid-loaded HA-based hydrogel on the components of the lamina propria. Representative images of H&E (A) and alcian blue (B) staining of each group (scale bars: A 400 μm, B 200 μm). C The composition of hyaluronic acid in the lamina propria was significantly increased in the SP group compared to the other groups. The intensity of alcian blue staining was measured and compared, except in the area of submucosal glands, using Image J software. ANOVA revealed that four groups showed significant difference (p = 0.009), while independent t-test did not attain statistical significance of two group comparison. Scale bar of A = 400 μm, B = 200 μm

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