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Fig. 5 | Biomaterials Research

Fig. 5

From: A methylprednisolone-loaded and core-shell nanofiber-covered stent-graft to prevent inflammation and reduce degradation in aortic dissection

Fig. 5

MPSS-loaded stent-grafts reduced inflammatory cells infiltration and expression of ICAM-1, VCAM-1 and P-selectin in endothelial cells. A Cell staining positive for MPO in each group, bar =100 μm; B Semi-quantitative analysis of MPO-positive cells in each group; C Cell staining positive for CD68 in each group, bar =100 μm; D Semi-quantitative analysis of CD68-positive cells in each group; E Cell staining positive for ICAM-1in each group, bar =100 μm; F Semi-quantitative analysis of ICAM-1-positive cells in each group. G Cell staining positive for VCAM-1 in each group, bar =100 μm; H Semi-quantitative analysis of VCAM-1-positive cells in each group. I Cell staining positive for P-selectin in each group, bar =100 μm; J Semi-quantitative analysis of P-selectin-positive cells in each group; K Western blotting of porcine aortic tissues for the relative expression of ICAM-1, VCAM-1 and P-selectin in each group; L, K and N Semi-quantitative analyses of ICAM-1/β-actin, VCAM-1/β-actin and P-selectin/β-actin in each group. The data are expressed as mean ± SD. Statistical significance:* P < 0.05; ** P < 0.01; *** P < 0.001. MOD, mean optical density

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