Skip to main content
Fig. 2 | Biomaterials Research

Fig. 2

From: A methylprednisolone-loaded and core-shell nanofiber-covered stent-graft to prevent inflammation and reduce degradation in aortic dissection

Fig. 2

In vitro cell proliferation, migration and inflammation tests on each nanofiber mesh. A HUVECs were treated with PLCL-N, MPSS-loaded with 0.2 mg, 0.4 mg, 0.6 mg, 0.8 mg and 1 mg for 24 h, the optical density (OD) values at 450 nm were measured and the cell proliferation was determined by CCK-8 assay; B The migration was determined by scratch wound assay after co-culture for 48 h and monitored through the use of digital photography at time of 0 h, 6 h and 24 h; C Rates of wound closure in each group at time of 6 h; D Rates of wound closure in each group at time of 24 h. E, F HUVECs were induced with LPS 100 ng/ml for 24 h, then treated with PLCL-N, MPSS-loaded with 0.2 mg, 0.4 mg, 0.6 mg, 0.8 mg and 1 mg for another 24 h. The supernatant of each group was collected to test the levels of tumor necrosis factor-α (TNF-α, E) and interluekin-6 (IL-6, F) by ELISA. The data are expressed as mean ± SD. Statistical significance:** P < 0.01 vs. control group; *** P < 0.001 vs. control group; ns P > 0.05 vs. control group. Ns indicates no significance

Back to article page