Table 13 Mutagenicity data, 4 h exposure, with metabolic activation
From: ISO 10993 biological evaluation of novel hemostatic powder – 4SEAL®
Sample | Number of large colonies | Number of small colonies | Mutant frequency (*10^-6) | Small colonies [%] | Small colonies mutant frequency (*10^-6) | Mutagenicity |
|---|---|---|---|---|---|---|
NC1 | 85 | 2 | 128.94 | 2.30 | 2.96 | N/A |
NC2 | 80 | 2 | 111.01 | 2.44 | 2.71 | N/A |
PC | 54 | 88 | 376.58 | 61.97 | 233.38 | Mutagenic |
4SEAL® 1 | 77 | 4 | 136.72 | 4.94 | 6.75 | Not Mutagenic |
4SEAL® 2 | 62 | 6 | 115.89 | 8.82 | 10.23 | Not Mutagenic |