Table 11 Toxicity data, 24 h exposure, without metabolic activation
From: ISO 10993 biological evaluation of novel hemostatic powder – 4SEAL®
Sample | Number of cells seeded (*10^5) | Number of cells 24 h after treatment (*10^5) | Number of cells 48 h after treatment (*10^5) | Total suspension growth | Relative Suspension Growth (RSG) [%] | Plating Efficiency [%] | Relative Plating Efficiency (RPE) [%] | Relative Total Growth (RTG) [%] |
|---|---|---|---|---|---|---|---|---|
NC1 | 2 | 11.18 | 9.73 | 130.95 | 100.00 | 90.82 | 100.00 | 100.00 |
NC2 | 2 | 10.95 | 9.62 | 129.57 | ||||
PC | 2 | 8.58 | 8.72 | 72.67 | 55.79 | 64.87 | 71.43 | 39.85 |
4SEAL® 1 | 2 | 10.79 | 8.96 | 108.52 | 83.31 | 86.64 | 95.41 | 79.49 |
4SEAL® 2 | 2 | 10.61 | 9.11 | 106.93 | 82.09 | 87.96 | 96.85 | 79.51 |