Fig. 2
Effect of SPIO-clustering on thermodynamic stability of PEG-PLA polymeric micelles. (A) Effect of SPIO clustering on CMC of PEG-PLA (5 k–5 k) polymeric micelles. CMC was determined form fluorescence intensities of pyrene (lem = 390 nm, lex = 333 nm) at different PEG-PLA concentrations. (B) Dissociation of SPIO-free micelles and SPIO-loaded micelles at the concentration of lower CMC (8 μg/mL) at 37 °C. Data are expressed as mean ± stdev, ** p < 0.05