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Fig. 5 | Biomaterials Research

Fig. 5

From: Treatment of bladder cancer by geoinspired synthetic chrysotile nanocarrier-delivered circPRMT5 siRNA

Fig. 5

In vivo imaging assessment of the biodistribution of SCNTs/FAM-si-circPRMT5. (A) In vivo images of mice bearing T24 tumors treated with SCNTs/FAM-si-circPRMT5 and other complexes after intratumoral injection at 2 h and 8 h. (B) Tumor site in vivo fluorescence intensity quantification after intratumoral injection at 2 h and 8 h. Data represent the mean ± SD (n = 5). (C-D) In vivo image of Cy5 accumulation in tumor and organs after intravenous injection of SCNTs/FAM-si-circPRMT5 and other complexes for 2 h (C) and 8 h (D). (E-F) Ex vivo fluorescence intensity quantification of control organs and tumors after intravenous injection at 2 h and 8 h. Data show represent mean ± SD (n = 5). **P < 0.01, ***P < 0.001

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Biomaterials Research

ISSN: 2055-7124

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