Table 1 IC₅₀ values and combination indices of Pt^(IV)-NP, SN38-NP, and nanococktails with varying drug molar ratios against human non-small cell lung cancer cell lines

9.64 ± 0.55

–

7.51 ± 0.36

–

0.39 ± 0.03

–

3.91 ± 0.69

–

Nanococktail (Pt-LA₂/SN38-LA, molar ratio)

10:1

1.15 ± 0.10

0.359

1.80 ± 0.07

0.287

5:1

0.82 ± 0.05

0.424

1.67 ± 0.05

0.271

2:1

0.81 ± 0.05

0.757

1.98 ± 0.07

0.400

1:1

0.66 ± 0.07

0.952

2.51 ± 0.12

0.550

1:2

0.65 ± 0.06

1.217

2.93 ± 0.15

0.635

1:5

0.67 ± 0.06

1.561

4.24 ± 0.44

1.025

1:10

0.52 ± 0.10

1.286

4.72 ± 0.81

1.316