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Table 2 Characters of aptamers conjugated with drugs

From: Design and clinical developments of aptamer-drug conjugates for targeted cancer therapy

Aptamer Type Target Conjugated drug References
P19 RNA PDAC Monomethyl auristatin E,
5-fluorouracil, gemcitabine
Yoo et al. (2017), Sora et al. (2016)
Sgc8 DNA PTK7 Doxorubicin Yu-Fen et al.(2009)
AS1411 DNA Nucleolin Doxorubicin, paclitaxel, triptolide Thu et al. (2015), Fangfei et al. (2017)
A10 RNA PSMA Doxorubicin, Vaishali et al. (2006)
Her2 aptamer RNA Her2 DM1(mertansine) Hwa et al. (2020)