Fig. 3
From: Design and clinical developments of aptamer-drug conjugates for targeted cancer therapy
(A) Chemical structure of gemcitabine monophosphate (dFdCMP) and 5-Fluorouracil monophosphate (5FdUMP), (B) dFdCMP (P19-dFdCMP) and 5FdUMP (P19–5FdUM) conjugated structure with P19 is indicated by a red dot representing dFdCMP and a blue dot representing 5FdUMP, (C) Chemical structure of MMAE (monomethyl auristatin E) conjugated with P19 by Linker and SE (Sticky sequence), (D) Chemical structure of DM1(maytansine 1) conjugated with P19 by linker and SE (Sticky sequence)