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Table 2 The quantitative analysis of micro-CT for the BMP-2 release profile on rat critical-sized calvarial defect model. Data was presented as mean ± SD. Cage N = 9, Cage+Biogel N = 11, Cage +BMP-2 N = 12, Cage+Biogel+BMP-2 N = 9

From: Three-dimensional printed polylactic acid scaffold integrated with BMP-2 laden hydrogel for precise bone regeneration

 

Cage

(N = 9)

Cage+Biogel

(N = 11)

Cage+BMP-2

(N = 12)

Cage+Biogel+BMP-2

(N = 9)

BV/TV

3.224 ± 2.503

2.945 ± 1.276

20.886 ± 7.67a,b

23.414 ± 4.518a,b

BS.BV

20.145 ± 2.36

19.631 ± 4.044

17.049 ± 2.918

16.73 ± 1.799

Tb.Th

0.195 ± 0.022

0.178 ± 0.034

0.194 ± 0.031

0.164 ± 0.012

Tb.Sp

1.74 ± 0.313

2.025 ± 0.282

0.701 ± 0.336a,b

0.726 ± 0.168a,b

Tb.N

0.166 ± 0.129

0.169 ± 0.077

1.104 ± 0.437a,b

1.434 ± 0.304a,b

Tb.Pf

5.023 ± 9.724

−6.693 ± 8.014

5.34 ± 15.973

−17.572 ± 4.28a,c

SMI

2.026 ± 2.021

−0.424 ± 1.697

1.935 ± 3.825

−3.962 ± 1.533a,b,c

DA

2 ± 0.473

2.275 ± 0.482

1.802 ± 0.207b

−1.718 ± 0.137b

  1. a compare with Cage group, p < 0.05
  2. b compare with Cage+Biogel group, p < 0.05
  3. c compare with Cage+BMP group, p < 0.05