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Fig. 4 | Biomaterials Research

Fig. 4

From: Three-dimensional printed polylactic acid scaffold integrated with BMP-2 laden hydrogel for precise bone regeneration

Fig. 4

In vivo result of rat calvaria. a PLA cage/BMP-2 group and PLA cage/Biogel/BMP-2 group both showed significant bone regeneration. Scale bar: 2 mm. b Cross-sectional images of rat calvaria. Both the groups with BMP-2 showed bone regeneration that bridged both edges of defect. Scale bar: 2 mm. c Histology sections of rat calvaria. The histology sections confirmed the results of micro-CT. Groups: 1, PLA cage group, N = 9; 2, PLA cage/Biogel group, N = 11; 3, PLA cage/BMP-2 group, N = 12; 4, PLA cage/Biogel/BMP-2 group, N = 9

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