Fig. 1
From: Polyphenols-loaded electrospun nanofibers in bone tissue engineering and regeneration
Demonstration of molecular signaling pathways of polyphenols involved in bone tissue regeneration. ROS- reactive oxygen species; p53- tumor suppressor; Gpx-1- glutathione peroxidase 1; SOD- superoxide dismutase; RANKL- receptor activator of nuclear factor kappa-Β ligand; NF-κB- nuclear factor kappa-light-chain-enhancer of activated B cells; NFATc1- nuclear factor of activated T cells 1; c-Fos- proto-oncogene; MAPKs- mitogen-activated protein kinases; MMPs- matrix metalloproteinases; ECM- extracellular matrix [13]