Fig. 4
From: The effects of the molecular weights of hyaluronic acid on the immune responses
Gene expression analysis in LPS-stimulated macrophages treated with various molecular weights of HyA using NanoString. A Heatmap presenting significantly differential expression levels of the 280 immune genes in LPS-stimulated macrophages. The data are presented in matrix format. The rows represent each gene and the columns represent the treatment group. Expression levels have been normalized within columns for visualization. The red and blue colors reflect high and low expression levels, respectively. B A scatter plot showing differential expression levels of the 280 immune genes in 12 samples compared to the untreated (control) group. Untreated: control; LMW-10: low molecular weight of HyA (10 kDa); MMW-100: medium molecular weight of HyA (100 kDa); MMW-500: medium molecular weight of HyA (500 kDa); HMW-1,500: high molecular weight of HyA (1,500 kDa). (Concentration of HyA, unit: µg/mL)