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Table 1 Characteristics of exosomes, microvesicles, and apoptotic bodies

From: Overcome the barriers of the skin: exosome therapy

 

Exosomes

Microvesicles

Apoptotic bodies

Ref

Size

40–100 nm

150–1000 nm

>  1000 nm

[16,17,18]

Composition

ProteinsLipids

RNAs

ProteinsLipids

RNAs

DNA fragments

Degraded proteins

Micronuclei

Cell organelles

[19, 20]

Origin

Multivesicular bodies

Plasma membrane

Plasma membrane, cellular fragments

[21]

Release

Exocytosis of MVBs

Budding from plasma membrane

Cell shrinkage and death

[21]