| Exosomes | Microvesicles | Apoptotic bodies | Ref |
---|---|---|---|---|
Size | 40–100 nm | 150–1000 nm | >  1000 nm | |
Composition | ProteinsLipids RNAs | ProteinsLipids RNAs | DNA fragments Degraded proteins Micronuclei Cell organelles | |
Origin | Multivesicular bodies | Plasma membrane | Plasma membrane, cellular fragments | [21] |
Release | Exocytosis of MVBs | Budding from plasma membrane | Cell shrinkage and death | [21] |