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Fig. 2 | Biomaterials Research

Fig. 2

From: In vivo tumour imaging employing regional delivery of novel gallium radiolabelled polymer composites

Fig. 2

Leach tests of 67Ga labelled MS in normal rabbit lungs. Polystyrene sulfonate MS (15 mg, 30 μm and 8 μm median diameter) were radiolabelled with 67Ga (avg. 87 MBq) using TA immobilisation. The suspensions in 5% dextrose (5 mL) were injected intravenously (ear vein) into anaesthetised rabbits and planar images of the rabbits were made 3 h post-injection using a GE Hawkeye Infinia SPECT-CT camera with a medium energy collimator and scatter correction. Control rabbits were injected intravenously with soluble 67Ga (avg. 87 MBq) for comparison of the biodistribution. Note pronounced lung retention of radiolabel using both 67GaTA-MS30 (a) and 67GaTA-MS8 (b), while soluble 67Ga citrate was systemically distributed with no lung definition (c)

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