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Fig. 10 | Biomaterials Research

Fig. 10

From: In vivo bone regeneration assessment of offset and gradient melt electrowritten (MEW) PCL scaffolds

Fig. 10

IHC analysis of Ocn in calvarial defect of rat 4 and 8 weeks of post-implantation of the MEW PCL scaffolds. a) Blank (defect control without implanted scaffold), 250 μm, 500 μm. b) Offset.50.50, Grad.750top, Grad.250top. Ocn: osteocalcin staining, Iso: Isotype control.. The white bar represents 200 μm. c) Quantitative analysis at weeks 4 and 8. The values expressed are the mean ± SD (n = 3). Statistically significant differences between mean Ocn intensity scores for the treatment groups when compared to the other groups were determined byby ANOVA (Significant: * p < 0.0001, ^ p = 0.004, ■ p < 0.0001, ♦ p = 0.006, p < 0.0001, p = 0.002)

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