TY - JOUR AU - Weiss-Bilka, Holly E. AU - Meagher, Matthew J. AU - Gargac, Joshua A. AU - Niebur, Glen L. AU - Roeder, Ryan K. AU - Wagner, Diane R. PY - 2019 DA - 2019/10/17 TI - Mineral deposition and vascular invasion of hydroxyapatite reinforced collagen scaffolds seeded with human adipose-derived stem cells JO - Biomaterials Research SP - 15 VL - 23 IS - 1 AB - Collagen-based scaffolds reinforced with hydroxyapatite (HA) are an attractive choice for bone tissue engineering because their composition mimics that of bone. We previously reported the development of compression-molded collagen-HA scaffolds that exhibited high porosity, interconnected pores, and mechanical properties that were well-suited for surgical handling and fixation. The objective of this study was to investigate these novel collagen-HA scaffolds in combination with human adipose-derived stem cells (hASCs) as a template for bone formation in a subcutaneous athymic mouse model. SN - 2055-7124 UR - https://doi.org/10.1186/s40824-019-0167-9 DO - 10.1186/s40824-019-0167-9 ID - Weiss-Bilka2019 ER -